| Moreno Valley to Southern Pines (North Carolina) | 2,139.69 mi (3,443.50 km) |
| Moreno Valley to Southfield (Michigan) | 1,920.75 mi (3,091.16 km) |
| Moreno Valley to Southgate (Michigan) | 1,921.48 mi (3,092.33 km) |
| Moreno Valley to Southlake (Texas) | 1,156.35 mi (1,860.97 km) |
| Moreno Valley to Spanaway (Washington) | 950.02 mi (1,528.91 km) |
| Moreno Valley to Spanish Fork (Utah) | 525.94 mi (846.41 km) |
| Moreno Valley to Spanish Lake (Missouri) | 1,533.35 mi (2,467.69 km) |
| Moreno Valley to Spanish Springs (Nevada) | 418.84 mi (674.07 km) |
| Moreno Valley to Sparks (Nevada) | 414.30 mi (666.75 km) |
| Moreno Valley to Spartanburg (South Carolina) | 2,001.22 mi (3,220.65 km) |
| Moreno Valley to Spearfish (South Dakota) | 1,020.55 mi (1,642.42 km) |
| Moreno Valley to Speedway (Indiana) | 1,749.35 mi (2,815.31 km) |
| Moreno Valley to Spencer (Iowa) | 1,345.58 mi (2,165.51 km) |
| Moreno Valley to Spokane (Washington) | 949.60 mi (1,528.24 km) |
| Moreno Valley to Spokane Valley (Washington) | 949.22 mi (1,527.62 km) |
