| Neu Isenburg to Oestrich-Winkel | 31.26 mi (50.31 km) |
| Neu Isenburg to Offenburg | 114.73 mi (184.64 km) |
| Neu Isenburg to Oftersheim | 47.22 mi (76.00 km) |
| Neu Isenburg to Ohrdruf | 104.36 mi (167.95 km) |
| Neu Isenburg to Ohringen | 68.78 mi (110.70 km) |
| Neu Isenburg to Olbernhau | 208.60 mi (335.71 km) |
| Neu Isenburg to Olching | 174.15 mi (280.27 km) |
| Neu Isenburg to Oldenburg | 214.78 mi (345.66 km) |
| Neu Isenburg to Oldenburg in Holstein | 307.83 mi (495.41 km) |
| Neu Isenburg to Olfen | 128.66 mi (207.06 km) |
| Neu Isenburg to Olpe | 76.88 mi (123.72 km) |
| Neu Isenburg to Olsberg | 90.32 mi (145.36 km) |
| Neu Isenburg to Oranienburg | 270.38 mi (435.13 km) |
| Neu Isenburg to Ortenberg | 26.33 mi (42.38 km) |
| Neu Isenburg to Oschatz | 211.38 mi (340.18 km) |
