| Neu Isenburg to Santeramo in Colle | 748.33 mi (1,204.32 km) |
| Neu Isenburg to Santo Stefano di Magra | 410.77 mi (661.06 km) |
| Neu Isenburg to Santo Stino di Livenza | 350.61 mi (564.26 km) |
| Neu Isenburg to Sarezzo | 311.85 mi (501.87 km) |
| Neu Isenburg to Sarno | 698.94 mi (1,124.84 km) |
| Neu Isenburg to Saronno | 306.10 mi (492.62 km) |
| Neu Isenburg to Sarzana | 414.41 mi (666.93 km) |
| Neu Isenburg to Sassari | 644.21 mi (1,036.76 km) |
| Neu Isenburg to Sasso Marconi | 408.24 mi (656.99 km) |
| Neu Isenburg to Sassuolo | 392.22 mi (631.22 km) |
| Neu Isenburg to Sava | 792.93 mi (1,276.10 km) |
| Neu Isenburg to Saviano | 690.58 mi (1,111.38 km) |
| Neu Isenburg to Savigliano | 376.42 mi (605.79 km) |
| Neu Isenburg to Savignano sul Panaro | 399.82 mi (643.45 km) |
| Neu Isenburg to Savignano sul Rubicone | 446.95 mi (719.30 km) |
