| Neu Isenburg to Savona | 396.87 mi (638.69 km) |
| Neu Isenburg to Scafati | 701.20 mi (1,128.48 km) |
| Neu Isenburg to Scalea | 786.87 mi (1,266.35 km) |
| Neu Isenburg to Scandiano | 388.36 mi (625.01 km) |
| Neu Isenburg to Scandicci | 450.51 mi (725.03 km) |
| Neu Isenburg to Schio | 324.01 mi (521.44 km) |
| Neu Isenburg to Sciacca | 893.31 mi (1,437.64 km) |
| Neu Isenburg to Scicli | 963.54 mi (1,550.67 km) |
| Neu Isenburg to Scordia | 932.20 mi (1,500.24 km) |
| Neu Isenburg to Scorze | 347.40 mi (559.09 km) |
| Neu Isenburg to Sedico | 313.74 mi (504.92 km) |
| Neu Isenburg to Sedriano | 315.77 mi (508.18 km) |
| Neu Isenburg to Segni | 613.99 mi (988.12 km) |
| Neu Isenburg to Segrate | 316.27 mi (508.99 km) |
| Neu Isenburg to Selargius | 746.29 mi (1,201.04 km) |
