| Neu Isenburg to Settimo Torinese | 342.48 mi (551.16 km) |
| Neu Isenburg to Seveso | 305.14 mi (491.08 km) |
| Neu Isenburg to Sezze | 626.83 mi (1,008.78 km) |
| Neu Isenburg to Siano | 701.39 mi (1,128.78 km) |
| Neu Isenburg to Siena | 481.47 mi (774.84 km) |
| Neu Isenburg to Signa | 447.49 mi (720.17 km) |
| Neu Isenburg to Silea | 346.36 mi (557.41 km) |
| Neu Isenburg to Silvi Paese | 578.75 mi (931.41 km) |
| Neu Isenburg to Sinalunga | 493.47 mi (794.16 km) |
| Neu Isenburg to Siniscola | 656.48 mi (1,056.50 km) |
| Neu Isenburg to Sinnai | 742.98 mi (1,195.71 km) |
| Neu Isenburg to Siracusa | 954.67 mi (1,536.40 km) |
| Neu Isenburg to Solaro | 306.94 mi (493.98 km) |
| Neu Isenburg to Soliera | 381.43 mi (613.86 km) |
| Neu Isenburg to Solofra | 702.56 mi (1,130.66 km) |
