| Neu Isenburg to Eemnes | 213.18 mi (343.07 km) |
| Neu Isenburg to Eerbeek | 182.37 mi (293.49 km) |
| Neu Isenburg to Eersel | 173.15 mi (278.66 km) |
| Neu Isenburg to Eijsden | 140.98 mi (226.89 km) |
| Neu Isenburg to Eindhoven | 170.02 mi (273.62 km) |
| Neu Isenburg to Elburg | 206.58 mi (332.46 km) |
| Neu Isenburg to Emmeloord | 223.44 mi (359.60 km) |
| Neu Isenburg to Emmen | 204.14 mi (328.54 km) |
| Neu Isenburg to Enkhuizen | 234.53 mi (377.43 km) |
| Neu Isenburg to Enschede | 168.81 mi (271.68 km) |
| Neu Isenburg to Epe | 197.68 mi (318.13 km) |
| Neu Isenburg to Ermelo | 204.92 mi (329.78 km) |
| Neu Isenburg to Etten-Leur | 206.13 mi (331.74 km) |
| Neu Isenburg to Franeker | 256.49 mi (412.79 km) |
| Neu Isenburg to Geertruidenberg | 202.56 mi (325.99 km) |
