| Neu Isenburg to Schijndel | 178.96 mi (288.02 km) |
| Neu Isenburg to Schinnen | 138.52 mi (222.92 km) |
| Neu Isenburg to Schoonhoven | 212.69 mi (342.29 km) |
| Neu Isenburg to Simpelveld | 131.21 mi (211.17 km) |
| Neu Isenburg to Sint Anthonis | 164.24 mi (264.32 km) |
| Neu Isenburg to Sint Willebrord | 207.15 mi (333.38 km) |
| Neu Isenburg to Sint-Michielsgestel | 182.64 mi (293.93 km) |
| Neu Isenburg to Sint-Oedenrode | 175.87 mi (283.04 km) |
| Neu Isenburg to Sittard | 140.69 mi (226.42 km) |
| Neu Isenburg to Sliedrecht | 210.27 mi (338.40 km) |
| Neu Isenburg to Slochteren | 233.46 mi (375.71 km) |
| Neu Isenburg to Sluis | 248.30 mi (399.59 km) |
| Neu Isenburg to Sneek | 243.94 mi (392.58 km) |
| Neu Isenburg to Soest | 208.46 mi (335.48 km) |
| Neu Isenburg to Someren | 159.73 mi (257.06 km) |
