| Neu Isenburg to Setubal | 1,174.11 mi (1,889.55 km) |
| Neu Isenburg to Sever do Vouga | 1,044.69 mi (1,681.26 km) |
| Neu Isenburg to Silves | 1,229.10 mi (1,978.04 km) |
| Neu Isenburg to Sines | 1,202.82 mi (1,935.75 km) |
| Neu Isenburg to Sintra | 1,178.02 mi (1,895.84 km) |
| Neu Isenburg to Sobrado de Paiva | 1,026.65 mi (1,652.23 km) |
| Neu Isenburg to Sobral de Monte Agraco | 1,158.30 mi (1,864.10 km) |
| Neu Isenburg to Soure | 1,087.77 mi (1,750.59 km) |
| Neu Isenburg to Tabua | 1,050.09 mi (1,689.95 km) |
| Neu Isenburg to Tavira | 1,206.39 mi (1,941.50 km) |
| Neu Isenburg to Tomar | 1,102.08 mi (1,773.62 km) |
| Neu Isenburg to Tondela | 1,044.47 mi (1,680.91 km) |
| Neu Isenburg to Torre de Moncorvo | 975.97 mi (1,570.67 km) |
| Neu Isenburg to Torres Novas | 1,113.04 mi (1,791.26 km) |
| Neu Isenburg to Torres Vedras | 1,159.22 mi (1,865.59 km) |
