| Neu Isenburg to Sangeorz-Bai | 750.12 mi (1,207.21 km) |
| Neu Isenburg to Sannicolau Mare | 614.28 mi (988.58 km) |
| Neu Isenburg to Santana | 641.45 mi (1,032.32 km) |
| Neu Isenburg to Satu Mare | 661.80 mi (1,065.06 km) |
| Neu Isenburg to Scobinti | 849.07 mi (1,366.45 km) |
| Neu Isenburg to Scornicesti | 831.21 mi (1,337.70 km) |
| Neu Isenburg to Sebes | 741.61 mi (1,193.50 km) |
| Neu Isenburg to Seini | 680.11 mi (1,094.53 km) |
| Neu Isenburg to Sfantu-Gheorghe | 839.61 mi (1,351.22 km) |
| Neu Isenburg to Sibiu | 771.75 mi (1,242.01 km) |
| Neu Isenburg to Sighetu Marmatiei | 702.92 mi (1,131.24 km) |
| Neu Isenburg to Sighisoara | 785.96 mi (1,264.88 km) |
| Neu Isenburg to Simeria | 721.51 mi (1,161.16 km) |
| Neu Isenburg to Sinaia | 845.85 mi (1,361.27 km) |
| Neu Isenburg to Slatina | 828.83 mi (1,333.87 km) |
