| Neu Isenburg to Ruzomberok | 479.69 mi (771.99 km) |
| Neu Isenburg to Sabinov | 558.05 mi (898.10 km) |
| Neu Isenburg to Sal'a | 435.09 mi (700.22 km) |
| Neu Isenburg to Samorin | 414.06 mi (666.37 km) |
| Neu Isenburg to Senec | 412.85 mi (664.42 km) |
| Neu Isenburg to Senica | 401.03 mi (645.39 km) |
| Neu Isenburg to Sered' | 425.45 mi (684.69 km) |
| Neu Isenburg to Skalica | 391.79 mi (630.52 km) |
| Neu Isenburg to Smizany | 535.55 mi (861.89 km) |
| Neu Isenburg to Snina | 607.20 mi (977.20 km) |
| Neu Isenburg to Spisska Nova Ves | 537.43 mi (864.90 km) |
| Neu Isenburg to Stara L'ubovna | 537.40 mi (864.86 km) |
| Neu Isenburg to Stara Tura | 413.58 mi (665.59 km) |
| Neu Isenburg to Stropkov | 581.84 mi (936.38 km) |
| Neu Isenburg to Stupava | 395.67 mi (636.76 km) |
