| Neu Isenburg to Olivenza | 1,102.71 mi (1,774.64 km) |
| Neu Isenburg to Olot | 619.17 mi (996.46 km) |
| Neu Isenburg to Onate | 715.66 mi (1,151.75 km) |
| Neu Isenburg to Onda | 821.80 mi (1,322.55 km) |
| Neu Isenburg to Onteniente | 899.89 mi (1,448.23 km) |
| Neu Isenburg to Orihuela | 953.56 mi (1,534.61 km) |
| Neu Isenburg to Osuna | 1,118.83 mi (1,800.59 km) |
| Neu Isenburg to Ourense | 951.47 mi (1,531.24 km) |
| Neu Isenburg to Oviedo | 827.58 mi (1,331.85 km) |
| Neu Isenburg to Paiporta | 858.16 mi (1,381.07 km) |
| Neu Isenburg to Pajara | 1,917.43 mi (3,085.80 km) |
| Neu Isenburg to Palafolls | 645.45 mi (1,038.76 km) |
| Neu Isenburg to Palafrugell | 621.19 mi (999.71 km) |
| Neu Isenburg to Palamos | 626.43 mi (1,008.14 km) |
| Neu Isenburg to Palencia | 841.00 mi (1,353.46 km) |
