| New Smyrna Beach to Orbetello | 5,000.20 mi (8,047.04 km) |
| New Smyrna Beach to Oria | 5,357.75 mi (8,622.46 km) |
| New Smyrna Beach to Oristano | 4,943.73 mi (7,956.17 km) |
| New Smyrna Beach to Orta Nova | 5,242.28 mi (8,436.63 km) |
| New Smyrna Beach to Orte | 5,054.33 mi (8,134.15 km) |
| New Smyrna Beach to Ortona | 5,150.78 mi (8,289.38 km) |
| New Smyrna Beach to Orvieto | 5,034.24 mi (8,101.83 km) |
| New Smyrna Beach to Orzinuovi | 4,862.54 mi (7,825.50 km) |
| New Smyrna Beach to Osimo | 5,075.65 mi (8,168.48 km) |
| New Smyrna Beach to Ospitaletto | 4,864.84 mi (7,829.20 km) |
| New Smyrna Beach to Ostuni | 5,347.94 mi (8,606.68 km) |
| New Smyrna Beach to Ottaviano | 5,199.21 mi (8,367.32 km) |
| New Smyrna Beach to Ovada | 4,823.42 mi (7,762.54 km) |
| New Smyrna Beach to Ozieri | 4,945.55 mi (7,959.09 km) |
| New Smyrna Beach to Paceco | 5,192.14 mi (8,355.94 km) |
