| New Smyrna Beach to Selargius | 4,989.27 mi (8,029.45 km) |
| New Smyrna Beach to Selvazzano Dentro | 4,945.96 mi (7,959.75 km) |
| New Smyrna Beach to Senago | 4,821.85 mi (7,760.01 km) |
| New Smyrna Beach to Senigallia | 5,057.01 mi (8,138.47 km) |
| New Smyrna Beach to Seravezza | 4,912.67 mi (7,906.18 km) |
| New Smyrna Beach to Seregno | 4,823.18 mi (7,762.15 km) |
| New Smyrna Beach to Seriate | 4,845.57 mi (7,798.19 km) |
| New Smyrna Beach to Sermoneta | 5,108.31 mi (8,221.03 km) |
| New Smyrna Beach to Serramanna | 4,972.93 mi (8,003.15 km) |
| New Smyrna Beach to Serravalle Pistoiese | 4,942.87 mi (7,954.79 km) |
| New Smyrna Beach to Sessa Aurunca | 5,162.19 mi (8,307.74 km) |
| New Smyrna Beach to Sesto Calende | 4,795.59 mi (7,717.75 km) |
| New Smyrna Beach to Sesto Fiorentino | 4,961.49 mi (7,984.74 km) |
| New Smyrna Beach to Sesto San Giovanni | 4,827.61 mi (7,769.28 km) |
| New Smyrna Beach to Sestri Levante | 4,866.97 mi (7,832.63 km) |
