| New Smyrna Beach to Sierpc | 5,055.52 mi (8,136.07 km) |
| New Smyrna Beach to Skarzysko-Kamienna | 5,158.00 mi (8,301.00 km) |
| New Smyrna Beach to Skawina | 5,151.53 mi (8,290.59 km) |
| New Smyrna Beach to Skierniewice | 5,101.93 mi (8,210.76 km) |
| New Smyrna Beach to Skoczow | 5,115.63 mi (8,232.80 km) |
| New Smyrna Beach to Skwierzyna | 4,905.32 mi (7,894.35 km) |
| New Smyrna Beach to Slawno | 4,901.47 mi (7,888.16 km) |
| New Smyrna Beach to Slubice | 4,875.88 mi (7,846.97 km) |
| New Smyrna Beach to Slupca | 5,004.75 mi (8,054.36 km) |
| New Smyrna Beach to Slupsk | 4,911.54 mi (7,904.37 km) |
| New Smyrna Beach to Sochaczew | 5,096.81 mi (8,202.52 km) |
| New Smyrna Beach to Sokolka | 5,180.06 mi (8,336.51 km) |
| New Smyrna Beach to Sokolow Podlaski | 5,167.13 mi (8,315.70 km) |
| New Smyrna Beach to Solec Kujawski | 4,995.77 mi (8,039.91 km) |
| New Smyrna Beach to Sopot | 4,968.27 mi (7,995.65 km) |
