| Newcastle under Lyme to Sceaux | 352.39 mi (567.11 km) |
| Newcastle under Lyme to Schiltigheim | 530.59 mi (853.90 km) |
| Newcastle under Lyme to Scionzier | 620.17 mi (998.07 km) |
| Newcastle under Lyme to Seclin | 281.76 mi (453.45 km) |
| Newcastle under Lyme to Sedan | 384.32 mi (618.50 km) |
| Newcastle under Lyme to Selestat | 535.71 mi (862.14 km) |
| Newcastle under Lyme to Sene | 373.17 mi (600.56 km) |
| Newcastle under Lyme to Senlis | 335.53 mi (539.99 km) |
| Newcastle under Lyme to Sens | 410.96 mi (661.38 km) |
| Newcastle under Lyme to Septemes-les-Vallons | 749.62 mi (1,206.39 km) |
| Newcastle under Lyme to Serris | 360.46 mi (580.10 km) |
| Newcastle under Lyme to Sete | 716.97 mi (1,153.85 km) |
| Newcastle under Lyme to Sevran | 349.53 mi (562.51 km) |
| Newcastle under Lyme to Sevres | 347.83 mi (559.77 km) |
| Newcastle under Lyme to Seynod | 617.16 mi (993.22 km) |
