| Newcastle under Lyme to Savignano sul Rubicone | 906.39 mi (1,458.69 km) |
| Newcastle under Lyme to Savona | 773.18 mi (1,244.31 km) |
| Newcastle under Lyme to Scafati | 1,153.35 mi (1,856.14 km) |
| Newcastle under Lyme to Scalea | 1,245.50 mi (2,004.44 km) |
| Newcastle under Lyme to Scandiano | 824.58 mi (1,327.03 km) |
| Newcastle under Lyme to Scandicci | 884.98 mi (1,424.24 km) |
| Newcastle under Lyme to Schio | 790.22 mi (1,271.73 km) |
| Newcastle under Lyme to Sciacca | 1,298.70 mi (2,090.05 km) |
| Newcastle under Lyme to Scicli | 1,386.22 mi (2,230.90 km) |
| Newcastle under Lyme to Scordia | 1,360.36 mi (2,189.28 km) |
| Newcastle under Lyme to Scorze | 823.02 mi (1,324.52 km) |
| Newcastle under Lyme to Sedico | 797.11 mi (1,282.82 km) |
| Newcastle under Lyme to Sedriano | 723.28 mi (1,164.01 km) |
| Newcastle under Lyme to Segni | 1,054.85 mi (1,697.62 km) |
| Newcastle under Lyme to Segrate | 733.24 mi (1,180.04 km) |
