| Newcastle under Lyme to Entroncamento | 981.35 mi (1,579.32 km) |
| Newcastle under Lyme to Ericeira | 1,028.97 mi (1,655.97 km) |
| Newcastle under Lyme to Ermezinde | 866.58 mi (1,394.62 km) |
| Newcastle under Lyme to Esmoriz | 885.04 mi (1,424.33 km) |
| Newcastle under Lyme to Espinho | 881.62 mi (1,418.84 km) |
| Newcastle under Lyme to Esposende | 849.62 mi (1,367.33 km) |
| Newcastle under Lyme to Estarreja | 897.61 mi (1,444.57 km) |
| Newcastle under Lyme to Estoril | 1,045.71 mi (1,682.90 km) |
| Newcastle under Lyme to Estremoz | 1,010.99 mi (1,627.03 km) |
| Newcastle under Lyme to Evora | 1,033.92 mi (1,663.94 km) |
| Newcastle under Lyme to Fafe | 845.26 mi (1,360.31 km) |
| Newcastle under Lyme to Falagueira | 1,039.44 mi (1,672.81 km) |
| Newcastle under Lyme to Famalicao | 852.91 mi (1,372.63 km) |
| Newcastle under Lyme to Fanzeres | 869.62 mi (1,399.52 km) |
| Newcastle under Lyme to Faro | 1,138.85 mi (1,832.79 km) |
