| Newcastle under Lyme to Santarem | 999.88 mi (1,609.15 km) |
| Newcastle under Lyme to Santiago do Cacem | 1,081.26 mi (1,740.12 km) |
| Newcastle under Lyme to Santo Andre | 1,079.72 mi (1,737.64 km) |
| Newcastle under Lyme to Santo Tirso | 857.60 mi (1,380.18 km) |
| Newcastle under Lyme to Sao Bras de Alportel | 1,129.20 mi (1,817.27 km) |
| Newcastle under Lyme to Sao Felix da Marinha | 879.78 mi (1,415.86 km) |
| Newcastle under Lyme to Sao Joao da Madeira | 886.70 mi (1,427.00 km) |
| Newcastle under Lyme to Sao Joao de Ver | 883.91 mi (1,422.52 km) |
| Newcastle under Lyme to Sao Mamede de Infesta | 868.49 mi (1,397.70 km) |
| Newcastle under Lyme to Sao Pedro do Sul | 890.15 mi (1,432.56 km) |
| Newcastle under Lyme to Satao | 886.60 mi (1,426.85 km) |
| Newcastle under Lyme to Seia | 906.98 mi (1,459.64 km) |
| Newcastle under Lyme to Senhora da Hora | 870.22 mi (1,400.49 km) |
| Newcastle under Lyme to Serpa | 1,072.24 mi (1,725.61 km) |
| Newcastle under Lyme to Serta | 953.89 mi (1,535.14 km) |
