| Newcastle under Lyme to Sangeorgiu de Mures | 1,262.88 mi (2,032.41 km) |
| Newcastle under Lyme to Sangeorz-Bai | 1,243.87 mi (2,001.81 km) |
| Newcastle under Lyme to Sannicolau Mare | 1,124.54 mi (1,809.78 km) |
| Newcastle under Lyme to Santana | 1,149.42 mi (1,849.82 km) |
| Newcastle under Lyme to Satu Mare | 1,156.56 mi (1,861.30 km) |
| Newcastle under Lyme to Scobinti | 1,336.55 mi (2,150.97 km) |
| Newcastle under Lyme to Scornicesti | 1,340.65 mi (2,157.56 km) |
| Newcastle under Lyme to Sebes | 1,247.57 mi (2,007.77 km) |
| Newcastle under Lyme to Seini | 1,174.18 mi (1,889.67 km) |
| Newcastle under Lyme to Sfantu-Gheorghe | 1,341.46 mi (2,158.87 km) |
| Newcastle under Lyme to Sibiu | 1,277.39 mi (2,055.76 km) |
| Newcastle under Lyme to Sighetu Marmatiei | 1,193.52 mi (1,920.78 km) |
| Newcastle under Lyme to Sighisoara | 1,287.96 mi (2,072.77 km) |
| Newcastle under Lyme to Simeria | 1,228.99 mi (1,977.86 km) |
| Newcastle under Lyme to Sinaia | 1,350.86 mi (2,173.99 km) |
