| Newcastle under Lyme to Santa Ursula | 1,847.81 mi (2,973.76 km) |
| Newcastle under Lyme to Santander | 663.65 mi (1,068.04 km) |
| Newcastle under Lyme to Santany | 977.06 mi (1,572.43 km) |
| Newcastle under Lyme to Santiago de Compostela | 757.99 mi (1,219.87 km) |
| Newcastle under Lyme to Santiago del Teide | 1,862.77 mi (2,997.84 km) |
| Newcastle under Lyme to Santiponce | 1,091.67 mi (1,756.88 km) |
| Newcastle under Lyme to Santomera | 1,034.43 mi (1,664.75 km) |
| Newcastle under Lyme to Santona | 663.58 mi (1,067.93 km) |
| Newcastle under Lyme to Santurce-Antiguo | 669.88 mi (1,078.06 km) |
| Newcastle under Lyme to Sarria | 745.93 mi (1,200.45 km) |
| Newcastle under Lyme to Sauzal | 1,843.13 mi (2,966.23 km) |
| Newcastle under Lyme to Sedavi | 942.59 mi (1,516.96 km) |
| Newcastle under Lyme to Segorbe | 912.89 mi (1,469.15 km) |
| Newcastle under Lyme to Segovia | 838.13 mi (1,348.84 km) |
| Newcastle under Lyme to Senmanat | 813.52 mi (1,309.24 km) |
