| Newcastle under Lyme to Cockermouth | 123.05 mi (198.03 km) |
| Newcastle under Lyme to Colchester | 152.82 mi (245.94 km) |
| Newcastle under Lyme to Coleford | 85.86 mi (138.18 km) |
| Newcastle under Lyme to Colne | 58.39 mi (93.97 km) |
| Newcastle under Lyme to Colwyn Bay | 63.98 mi (102.96 km) |
| Newcastle under Lyme to Congleton | 10.45 mi (16.82 km) |
| Newcastle under Lyme to Conisbrough | 52.52 mi (84.52 km) |
| Newcastle under Lyme to Connahs Quay | 37.25 mi (59.94 km) |
| Newcastle under Lyme to Consett | 128.10 mi (206.15 km) |
| Newcastle under Lyme to Conwy | 68.95 mi (110.96 km) |
| Newcastle under Lyme to Cookstown | 216.06 mi (347.72 km) |
| Newcastle under Lyme to Corby | 73.36 mi (118.07 km) |
| Newcastle under Lyme to Corfe Mullen | 155.08 mi (249.58 km) |
| Newcastle under Lyme to Corsham | 108.97 mi (175.37 km) |
| Newcastle under Lyme to Coseley | 32.41 mi (52.17 km) |
