| Newcastle under Lyme to East Dereham | 134.13 mi (215.86 km) |
| Newcastle under Lyme to East Finchley | 130.97 mi (210.78 km) |
| Newcastle under Lyme to East Grinstead | 160.74 mi (258.68 km) |
| Newcastle under Lyme to East Ham | 140.54 mi (226.18 km) |
| Newcastle under Lyme to East Kilbride | 205.76 mi (331.13 km) |
| Newcastle under Lyme to East Retford | 57.41 mi (92.39 km) |
| Newcastle under Lyme to Eastbourne | 188.15 mi (302.79 km) |
| Newcastle under Lyme to Eastham | 36.89 mi (59.36 km) |
| Newcastle under Lyme to Eastleigh | 146.09 mi (235.11 km) |
| Newcastle under Lyme to Eastwood | 38.40 mi (61.80 km) |
| Newcastle under Lyme to Ebbw Vale | 94.59 mi (152.23 km) |
| Newcastle under Lyme to Eccles | 32.90 mi (52.95 km) |
| Newcastle under Lyme to Ecclesall | 38.75 mi (62.36 km) |
| Newcastle under Lyme to Ecclesfield | 43.29 mi (69.67 km) |
| Newcastle under Lyme to Eccleston | 38.06 mi (61.25 km) |
