| Newcastle under Lyme to Sunbury | 133.66 mi (215.10 km) |
| Newcastle under Lyme to Sunderland | 135.39 mi (217.88 km) |
| Newcastle under Lyme to Sunninghill | 129.55 mi (208.49 km) |
| Newcastle under Lyme to Surbiton | 138.18 mi (222.38 km) |
| Newcastle under Lyme to Sutton | 142.56 mi (229.43 km) |
| Newcastle under Lyme to Sutton Coldfield | 35.29 mi (56.79 km) |
| Newcastle under Lyme to Sutton in Ashfield | 40.90 mi (65.83 km) |
| Newcastle under Lyme to Sutton on Hull | 95.42 mi (153.56 km) |
| Newcastle under Lyme to Swadlincote | 32.40 mi (52.14 km) |
| Newcastle under Lyme to Swallownest | 44.57 mi (71.72 km) |
| Newcastle under Lyme to Swanage | 166.42 mi (267.82 km) |
| Newcastle under Lyme to Swindon | 102.02 mi (164.18 km) |
| Newcastle under Lyme to Swinton | 50.10 mi (80.62 km) |
| Newcastle under Lyme to Swinton | 34.95 mi (56.25 km) |
| Newcastle under Lyme to Syston | 52.48 mi (84.46 km) |
