| Newcastle under Lyme to Emeryville (California) | 5,210.20 mi (8,385.01 km) |
| Newcastle under Lyme to Emmaus (Pennsylvania) | 3,413.34 mi (5,493.23 km) |
| Newcastle under Lyme to Emporia (Kansas) | 4,310.22 mi (6,936.62 km) |
| Newcastle under Lyme to Encinitas (California) | 5,331.33 mi (8,579.94 km) |
| Newcastle under Lyme to Endicott (New York) | 3,366.10 mi (5,417.21 km) |
| Newcastle under Lyme to Endwell (New York) | 3,363.54 mi (5,413.10 km) |
| Newcastle under Lyme to Englewood (Colorado) | 4,557.84 mi (7,335.13 km) |
| Newcastle under Lyme to Englewood (Florida) | 4,351.78 mi (7,003.51 km) |
| Newcastle under Lyme to Englewood (New Jersey) | 3,336.55 mi (5,369.66 km) |
| Newcastle under Lyme to Englewood (Ohio) | 3,790.27 mi (6,099.84 km) |
| Newcastle under Lyme to Enid (Oklahoma) | 4,474.28 mi (7,200.67 km) |
| Newcastle under Lyme to Ennis (Texas) | 4,640.79 mi (7,468.63 km) |
| Newcastle under Lyme to Ensley (Florida) | 4,368.51 mi (7,030.44 km) |
| Newcastle under Lyme to Enterprise (Alabama) | 4,270.56 mi (6,872.81 km) |
| Newcastle under Lyme to Enterprise (Nevada) | 5,097.29 mi (8,203.29 km) |
