| Newcastle under Lyme to Oswego (Illinois) | 3,857.39 mi (6,207.87 km) |
| Newcastle under Lyme to Oswego (New York) | 3,323.95 mi (5,349.38 km) |
| Newcastle under Lyme to Otsego (Minnesota) | 3,879.07 mi (6,242.77 km) |
| Newcastle under Lyme to Ottawa (Illinois) | 3,891.33 mi (6,262.49 km) |
| Newcastle under Lyme to Ottawa (Kansas) | 4,266.07 mi (6,865.58 km) |
| Newcastle under Lyme to Ottumwa (Iowa) | 4,040.93 mi (6,503.24 km) |
| Newcastle under Lyme to Overland (Missouri) | 4,078.49 mi (6,563.70 km) |
| Newcastle under Lyme to Overland Park (Kansas) | 4,230.34 mi (6,808.07 km) |
| Newcastle under Lyme to Overlea (Maryland) | 3,507.23 mi (5,644.34 km) |
| Newcastle under Lyme to Oviedo (Florida) | 4,217.58 mi (6,787.54 km) |
| Newcastle under Lyme to Owasso (Oklahoma) | 4,404.85 mi (7,088.92 km) |
| Newcastle under Lyme to Owatonna (Minnesota) | 3,921.46 mi (6,310.99 km) |
| Newcastle under Lyme to Owensboro (Kentucky) | 4,000.20 mi (6,437.69 km) |
| Newcastle under Lyme to Owings Mills (Maryland) | 3,515.99 mi (5,658.44 km) |
| Newcastle under Lyme to Owosso (Michigan) | 3,639.47 mi (5,857.17 km) |
