| Newcastle under Lyme to Scottsboro (Alabama) | 4,111.95 mi (6,617.54 km) |
| Newcastle under Lyme to Scottsdale (Arizona) | 5,116.40 mi (8,234.05 km) |
| Newcastle under Lyme to Scranton (Pennsylvania) | 3,381.08 mi (5,441.32 km) |
| Newcastle under Lyme to Seabrook (Maryland) | 3,538.19 mi (5,694.17 km) |
| Newcastle under Lyme to Seabrook (Texas) | 4,723.48 mi (7,601.71 km) |
| Newcastle under Lyme to Seaford (New York) | 3,327.24 mi (5,354.68 km) |
| Newcastle under Lyme to Seagoville (Texas) | 4,620.24 mi (7,435.55 km) |
| Newcastle under Lyme to Seal Beach (California) | 5,316.95 mi (8,556.80 km) |
| Newcastle under Lyme to Searcy (Arkansas) | 4,303.24 mi (6,925.39 km) |
| Newcastle under Lyme to Seaside (California) | 5,266.98 mi (8,476.38 km) |
| Newcastle under Lyme to SeaTac (Washington) | 4,656.07 mi (7,493.21 km) |
| Newcastle under Lyme to Seattle (Washington) | 4,646.67 mi (7,478.09 km) |
| Newcastle under Lyme to Sebastian (Florida) | 4,233.41 mi (6,813.01 km) |
| Newcastle under Lyme to Sebring (Florida) | 4,288.90 mi (6,902.32 km) |
| Newcastle under Lyme to Secaucus (New Jersey) | 3,345.17 mi (5,383.53 km) |
