| Newcastle under Lyme to St. George (Utah) | 4,983.93 mi (8,020.87 km) |
| Newcastle under Lyme to St. Helens (Oregon) | 4,760.70 mi (7,661.60 km) |
| Newcastle under Lyme to St. James (New York) | 3,304.36 mi (5,317.85 km) |
| Newcastle under Lyme to St. John (Indiana) | 3,836.23 mi (6,173.82 km) |
| Newcastle under Lyme to St. Joseph (Missouri) | 4,191.47 mi (6,745.53 km) |
| Newcastle under Lyme to St. Louis (Missouri) | 4,076.80 mi (6,560.97 km) |
| Newcastle under Lyme to St. Louis Park (Minnesota) | 3,885.18 mi (6,252.60 km) |
| Newcastle under Lyme to St. Marys (Georgia) | 4,126.93 mi (6,641.65 km) |
| Newcastle under Lyme to St. Marys (Pennsylvania) | 3,491.83 mi (5,619.56 km) |
| Newcastle under Lyme to St. Matthews (Kentucky) | 3,919.03 mi (6,307.07 km) |
| Newcastle under Lyme to St. Michael (Minnesota) | 3,884.69 mi (6,251.80 km) |
| Newcastle under Lyme to St. Paul (Minnesota) | 3,875.99 mi (6,237.80 km) |
| Newcastle under Lyme to St. Peter (Minnesota) | 3,936.14 mi (6,334.61 km) |
| Newcastle under Lyme to St. Peters (Missouri) | 4,083.22 mi (6,571.31 km) |
| Newcastle under Lyme to St. Petersburg (Florida) | 4,322.29 mi (6,956.05 km) |
