| Newcastle under Lyme to Storm Lake (Iowa) | 4,061.98 mi (6,537.13 km) |
| Newcastle under Lyme to Storrs (Connecticut) | 3,227.35 mi (5,193.92 km) |
| Newcastle under Lyme to Stoughton (Wisconsin) | 3,831.51 mi (6,166.21 km) |
| Newcastle under Lyme to Stow (Ohio) | 3,617.77 mi (5,822.24 km) |
| Newcastle under Lyme to Streamwood (Illinois) | 3,835.42 mi (6,172.51 km) |
| Newcastle under Lyme to Streator (Illinois) | 3,902.52 mi (6,280.51 km) |
| Newcastle under Lyme to Streetsboro (Ohio) | 3,611.43 mi (5,812.03 km) |
| Newcastle under Lyme to Strongsville (Ohio) | 3,626.89 mi (5,836.92 km) |
| Newcastle under Lyme to Stuart (Florida) | 4,253.70 mi (6,845.67 km) |
| Newcastle under Lyme to Stuarts Draft (Virginia) | 3,670.23 mi (5,906.67 km) |
| Newcastle under Lyme to Sturgis (Michigan) | 3,741.89 mi (6,022.00 km) |
| Newcastle under Lyme to Suamico (Wisconsin) | 3,709.15 mi (5,969.29 km) |
| Newcastle under Lyme to Sudley (Virginia) | 3,572.90 mi (5,750.03 km) |
| Newcastle under Lyme to Suffern (New York) | 3,333.42 mi (5,364.63 km) |
| Newcastle under Lyme to Suffolk (Virginia) | 3,636.49 mi (5,852.37 km) |
