| Niagara Falls to St. Louis (Missouri) | 661.91 mi (1,065.24 km) |
| Niagara Falls to Atlanta (Georgia) | 707.52 mi (1,138.65 km) |
| Niagara Falls to Minneapolis (Minnesota) | 718.79 mi (1,156.78 km) |
| Niagara Falls to Tampa (Florida) | 1,060.56 mi (1,706.80 km) |
| Niagara Falls to Dallas (Texas) | 1,196.66 mi (1,925.83 km) |
| Niagara Falls to Miami (Florida) | 1,197.78 mi (1,927.64 km) |
| Niagara Falls to Houston (Texas) | 1,289.08 mi (2,074.57 km) |
| Niagara Falls to Denver (Colorado) | 1,353.80 mi (2,178.72 km) |
| Niagara Falls to Phoenix (Arizona) | 1,894.69 mi (3,049.21 km) |
| Niagara Falls to Las Vegas (Nevada) | 1,969.07 mi (3,168.91 km) |
| Niagara Falls to Seattle (Washington) | 2,097.99 mi (3,376.39 km) |
| Niagara Falls to Portland (Oregon) | 2,137.14 mi (3,439.40 km) |
| Niagara Falls to Riverside (California) | 2,148.21 mi (3,457.20 km) |
| Niagara Falls to San Diego (California) | 2,172.06 mi (3,495.59 km) |
| Niagara Falls to Los Angeles (California) | 2,193.38 mi (3,529.90 km) |
| Niagara Falls to San Francisco (California) | 2,287.91 mi (3,682.03 km) |
| Niagara Falls to Detroit (Michigan) | 213.11 mi (342.97 km) |
| Niagara Falls to Baltimore (Maryland) | 289.86 mi (466.48 km) |
| Niagara Falls to Philadelphia (Pennsylvania) | 292.65 mi (470.98 km) |
| Niagara Falls to Washington (District of Columbia) | 307.49 mi (494.86 km) |
| Niagara Falls to New York (New York) | 309.71 mi (498.43 km) |
| Niagara Falls to Brooklyn (New York) | 310.36 mi (499.48 km) |
| Niagara Falls to Queens (New York) | 313.16 mi (503.99 km) |
| Niagara Falls to Boston (Massachusetts) | 405.98 mi (653.36 km) |
| Niagara Falls to Chicago (Illinois) | 450.20 mi (724.53 km) |
