| Niles to Elyria (Ohio) | 297.61 mi (478.96 km) |
| Niles to Emeryville (California) | 1,837.03 mi (2,956.42 km) |
| Niles to Emmaus (Pennsylvania) | 646.95 mi (1,041.16 km) |
| Niles to Emporia (Kansas) | 507.96 mi (817.48 km) |
| Niles to Encinitas (California) | 1,718.13 mi (2,765.07 km) |
| Niles to Endicott (New York) | 602.06 mi (968.93 km) |
| Niles to Endwell (New York) | 604.13 mi (972.25 km) |
| Niles to Englewood (Colorado) | 911.60 mi (1,467.08 km) |
| Niles to Englewood (Florida) | 1,085.07 mi (1,746.25 km) |
| Niles to Englewood (New Jersey) | 719.93 mi (1,158.62 km) |
| Niles to Englewood (Ohio) | 236.11 mi (379.98 km) |
| Niles to Enid (Oklahoma) | 663.23 mi (1,067.36 km) |
| Niles to Ennis (Texas) | 826.87 mi (1,330.71 km) |
| Niles to Ensley (Florida) | 795.26 mi (1,279.85 km) |
| Niles to Enterprise (Alabama) | 747.22 mi (1,202.54 km) |
