| Niles to Scottsboro (Alabama) | 519.00 mi (835.25 km) |
| Niles to Scottsdale (Arizona) | 1,426.86 mi (2,296.31 km) |
| Niles to Scranton (Pennsylvania) | 627.33 mi (1,009.58 km) |
| Niles to Seabrook (Maryland) | 612.52 mi (985.76 km) |
| Niles to Seabrook (Texas) | 949.72 mi (1,528.42 km) |
| Niles to Seaford (New York) | 747.67 mi (1,203.26 km) |
| Niles to Seagoville (Texas) | 805.15 mi (1,295.76 km) |
| Niles to Seal Beach (California) | 1,735.50 mi (2,793.01 km) |
| Niles to Searcy (Arkansas) | 514.35 mi (827.77 km) |
| Niles to Seaside (California) | 1,843.03 mi (2,966.07 km) |
| Niles to SeaTac (Washington) | 1,718.61 mi (2,765.84 km) |
| Niles to Seattle (Washington) | 1,719.80 mi (2,767.76 km) |
| Niles to Sebastian (Florida) | 1,067.21 mi (1,717.51 km) |
| Niles to Sebring (Florida) | 1,067.34 mi (1,717.72 km) |
| Niles to Secaucus (New Jersey) | 716.67 mi (1,153.37 km) |
