| Niles to Southern Pines (North Carolina) | 654.33 mi (1,053.04 km) |
| Niles to Southfield (Michigan) | 234.69 mi (377.70 km) |
| Niles to Southgate (Michigan) | 236.26 mi (380.23 km) |
| Niles to Southlake (Texas) | 808.38 mi (1,300.96 km) |
| Niles to Spanaway (Washington) | 1,724.73 mi (2,775.69 km) |
| Niles to Spanish Fork (Utah) | 1,244.34 mi (2,002.58 km) |
| Niles to Spanish Lake (Missouri) | 256.90 mi (413.43 km) |
| Niles to Spanish Springs (Nevada) | 1,663.67 mi (2,677.41 km) |
| Niles to Sparks (Nevada) | 1,667.65 mi (2,683.83 km) |
| Niles to Spartanburg (South Carolina) | 583.46 mi (938.99 km) |
| Niles to Spearfish (South Dakota) | 821.72 mi (1,322.43 km) |
| Niles to Speedway (Indiana) | 174.57 mi (280.94 km) |
| Niles to Spencer (Iowa) | 381.34 mi (613.71 km) |
| Niles to Spokane (Washington) | 1,492.42 mi (2,401.81 km) |
| Niles to Spokane Valley (Washington) | 1,483.19 mi (2,386.96 km) |
