| Niles to Superior (Colorado) | 914.78 mi (1,472.20 km) |
| Niles to Superior (Wisconsin) | 385.21 mi (619.93 km) |
| Niles to Surprise (Arizona) | 1,456.05 mi (2,343.29 km) |
| Niles to Susanville (California) | 1,697.88 mi (2,732.47 km) |
| Niles to Sussex (Wisconsin) | 79.30 mi (127.62 km) |
| Niles to Suwanee (Georgia) | 587.39 mi (945.31 km) |
| Niles to Swansea (Illinois) | 266.19 mi (428.38 km) |
| Niles to Sweetwater (Florida) | 1,199.70 mi (1,930.72 km) |
| Niles to Sweetwater (Texas) | 955.30 mi (1,537.41 km) |
| Niles to Sycamore (Illinois) | 44.83 mi (72.15 km) |
| Niles to Sylacauga (Alabama) | 617.28 mi (993.42 km) |
| Niles to Sylvania (Ohio) | 212.11 mi (341.35 km) |
| Niles to Syosset (New York) | 745.13 mi (1,199.16 km) |
| Niles to Syracuse (New York) | 597.58 mi (961.71 km) |
| Niles to Syracuse (Utah) | 1,251.78 mi (2,014.54 km) |
