| North Hykeham to Sacile | 767.62 mi (1,235.37 km) |
| North Hykeham to Sala Consilina | 1,163.48 mi (1,872.44 km) |
| North Hykeham to Salemi | 1,239.45 mi (1,994.70 km) |
| North Hykeham to Salerno | 1,122.34 mi (1,806.23 km) |
| North Hykeham to Salo | 722.73 mi (1,163.13 km) |
| North Hykeham to Salsomaggiore Terme | 749.25 mi (1,205.80 km) |
| North Hykeham to Saluzzo | 693.68 mi (1,116.37 km) |
| North Hykeham to Salzano | 776.53 mi (1,249.71 km) |
| North Hykeham to Samarate | 670.31 mi (1,078.76 km) |
| North Hykeham to San Benedetto del Tronto | 969.24 mi (1,559.85 km) |
| North Hykeham to San Biagio di Callalta | 777.53 mi (1,251.31 km) |
| North Hykeham to San Bonifacio | 756.67 mi (1,217.74 km) |
| North Hykeham to San Casciano in Val di Pesa | 849.05 mi (1,366.41 km) |
| North Hykeham to San Cataldo | 1,289.73 mi (2,075.62 km) |
| North Hykeham to San Cesareo | 1,000.23 mi (1,609.72 km) |
