| North Tonawanda to Sacile | 4,242.64 mi (6,827.86 km) |
| North Tonawanda to Sala Consilina | 4,593.37 mi (7,392.31 km) |
| North Tonawanda to Salemi | 4,581.82 mi (7,373.72 km) |
| North Tonawanda to Salerno | 4,546.49 mi (7,316.87 km) |
| North Tonawanda to Salo | 4,177.31 mi (6,722.73 km) |
| North Tonawanda to Salsomaggiore Terme | 4,184.16 mi (6,733.75 km) |
| North Tonawanda to Saluzzo | 4,087.28 mi (6,577.84 km) |
| North Tonawanda to Salzano | 4,243.87 mi (6,829.84 km) |
| North Tonawanda to Samarate | 4,105.29 mi (6,606.82 km) |
| North Tonawanda to San Benedetto del Tronto | 4,417.32 mi (7,108.99 km) |
| North Tonawanda to San Biagio di Callalta | 4,248.63 mi (6,837.51 km) |
| North Tonawanda to San Bonifacio | 4,215.28 mi (6,783.84 km) |
| North Tonawanda to San Casciano in Val di Pesa | 4,278.12 mi (6,884.96 km) |
| North Tonawanda to San Cataldo | 4,647.24 mi (7,479.00 km) |
| North Tonawanda to San Cesareo | 4,417.98 mi (7,110.05 km) |
