| Miami (Florida) to Picayune | 662.84 mi (1,066.73 km) |
| Chicago (Illinois) to Picayune | 788.87 mi (1,269.56 km) |
| Detroit (Michigan) to Picayune | 895.82 mi (1,441.68 km) |
| Washington (District of Columbia) to Picayune | 921.05 mi (1,482.29 km) |
| Baltimore (Maryland) to Picayune | 954.61 mi (1,536.30 km) |
| Minneapolis (Minnesota) to Picayune | 1,015.99 mi (1,635.07 km) |
| Philadelphia (Pennsylvania) to Picayune | 1,046.99 mi (1,684.96 km) |
| Denver (Colorado) to Picayune | 1,067.25 mi (1,717.58 km) |
| Brooklyn (New York) to Picayune | 1,123.52 mi (1,808.12 km) |
| New York (New York) to Picayune | 1,126.28 mi (1,812.58 km) |
| Queens (New York) to Picayune | 1,133.96 mi (1,824.93 km) |
| Boston (Massachusetts) to Picayune | 1,310.63 mi (2,109.25 km) |
| Phoenix (Arizona) to Picayune | 1,326.76 mi (2,135.22 km) |
| Las Vegas (Nevada) to Picayune | 1,523.20 mi (2,451.35 km) |
| San Diego (California) to Picayune | 1,617.22 mi (2,602.67 km) |
| Riverside (California) to Picayune | 1,632.16 mi (2,626.71 km) |
| Los Angeles (California) to Picayune | 1,690.21 mi (2,720.14 km) |
| San Francisco (California) to Picayune | 1,928.55 mi (3,103.70 km) |
| Portland (Oregon) to Picayune | 2,051.54 mi (3,301.64 km) |
| Seattle (Washington) to Picayune | 2,088.01 mi (3,360.32 km) |
| Houston (Texas) to Picayune | 345.31 mi (555.73 km) |
| Atlanta (Georgia) to Picayune | 379.59 mi (610.90 km) |
| Dallas (Texas) to Picayune | 445.38 mi (716.77 km) |
| Tampa (Florida) to Picayune | 469.49 mi (755.57 km) |
| St. Louis (Missouri) to Picayune | 560.85 mi (902.61 km) |
