| Opelika to Altus (Oklahoma) | 812.15 mi (1,307.03 km) |
| Opelika to Alum Rock (California) | 2,074.90 mi (3,339.22 km) |
| Opelika to Alvin (Texas) | 628.90 mi (1,012.12 km) |
| Opelika to Amarillo (Texas) | 958.29 mi (1,542.22 km) |
| Opelika to Amelia (Ohio) | 444.55 mi (715.43 km) |
| Opelika to American Canyon (California) | 2,097.18 mi (3,375.08 km) |
| Opelika to American Fork (Utah) | 1,553.68 mi (2,500.40 km) |
| Opelika to Americus (Georgia) | 78.54 mi (126.40 km) |
| Opelika to Ames (Iowa) | 788.89 mi (1,269.60 km) |
| Opelika to Amherst (Ohio) | 628.26 mi (1,011.09 km) |
| Opelika to Ammon (Idaho) | 1,617.58 mi (2,603.24 km) |
| Opelika to Amsterdam (New York) | 935.02 mi (1,504.77 km) |
| Opelika to Anacortes (Washington) | 2,209.47 mi (3,555.79 km) |
| Opelika to Anaheim (California) | 1,870.75 mi (3,010.69 km) |
| Opelika to Anchorage (Alaska) | 3,404.37 mi (5,478.80 km) |
