| Opelika to Clarksdale (Mississippi) | 317.53 mi (511.01 km) |
| Opelika to Clarkston (Georgia) | 103.12 mi (165.95 km) |
| Opelika to Clarksville (Indiana) | 391.74 mi (630.44 km) |
| Opelika to Clarksville (Tennessee) | 292.19 mi (470.23 km) |
| Opelika to Clawson (Michigan) | 693.06 mi (1,115.37 km) |
| Opelika to Clay (Alabama) | 100.89 mi (162.37 km) |
| Opelika to Clayton (California) | 2,079.62 mi (3,346.82 km) |
| Opelika to Clayton (Missouri) | 498.04 mi (801.51 km) |
| Opelika to Clayton (North Carolina) | 446.77 mi (719.01 km) |
| Opelika to Clayton (Ohio) | 501.40 mi (806.93 km) |
| Opelika to Clearfield (Utah) | 1,576.11 mi (2,536.50 km) |
| Opelika to Clearlake (California) | 2,117.09 mi (3,407.12 km) |
| Opelika to Clearwater (Florida) | 359.09 mi (577.90 km) |
| Opelika to Cleburne (Texas) | 701.37 mi (1,128.74 km) |
| Opelika to Clemmons (North Carolina) | 367.73 mi (591.80 km) |
