| Opelika to Darby (Pennsylvania) | 753.38 mi (1,212.45 km) |
| Opelika to Dardenne Prairie (Missouri) | 517.09 mi (832.18 km) |
| Opelika to Darien (Illinois) | 643.69 mi (1,035.92 km) |
| Opelika to Davenport (Iowa) | 678.43 mi (1,091.82 km) |
| Opelika to Davidson (North Carolina) | 325.38 mi (523.65 km) |
| Opelika to Davie (Florida) | 548.22 mi (882.28 km) |
| Opelika to Davis (California) | 2,068.75 mi (3,329.33 km) |
| Opelika to Dayton (Nevada) | 1,953.21 mi (3,143.39 km) |
| Opelika to Dayton (Ohio) | 496.23 mi (798.61 km) |
| Opelika to Daytona Beach (Florida) | 348.52 mi (560.89 km) |
| Opelika to De Pere (Wisconsin) | 826.07 mi (1,329.43 km) |
| Opelika to De Witt (New York) | 876.50 mi (1,410.59 km) |
| Opelika to Dearborn (Michigan) | 677.26 mi (1,089.94 km) |
| Opelika to Dearborn Heights (Michigan) | 676.91 mi (1,089.38 km) |
| Opelika to DeBary (Florida) | 355.02 mi (571.35 km) |
