| Opelika to Delaware (Ohio) | 542.02 mi (872.29 km) |
| Opelika to Delhi (California) | 2,017.28 mi (3,246.50 km) |
| Opelika to Delray Beach (Florida) | 533.49 mi (858.57 km) |
| Opelika to Deltona (Florida) | 358.29 mi (576.61 km) |
| Opelika to Deming (New Mexico) | 1,302.31 mi (2,095.86 km) |
| Opelika to Denison (Texas) | 651.81 mi (1,048.98 km) |
| Opelika to Dent (Ohio) | 452.97 mi (728.99 km) |
| Opelika to Denton (Texas) | 682.92 mi (1,099.06 km) |
| Opelika to Dentsville (South Carolina) | 273.21 mi (439.69 km) |
| Opelika to Denver (Colorado) | 1,189.26 mi (1,913.93 km) |
| Opelika to Depew (New York) | 795.81 mi (1,280.74 km) |
| Opelika to Derby (Connecticut) | 903.16 mi (1,453.49 km) |
| Opelika to Derby (Kansas) | 750.98 mi (1,208.58 km) |
| Opelika to Des Moines (Iowa) | 763.95 mi (1,229.46 km) |
| Opelika to Des Moines (Washington) | 2,175.72 mi (3,501.48 km) |
