| Opelika to Duluth (Minnesota) | 1,038.33 mi (1,671.03 km) |
| Opelika to Dumas (Texas) | 971.35 mi (1,563.24 km) |
| Opelika to Dumont (New Jersey) | 849.69 mi (1,367.44 km) |
| Opelika to Duncan (Oklahoma) | 733.00 mi (1,179.65 km) |
| Opelika to Duncanville (Texas) | 670.74 mi (1,079.45 km) |
| Opelika to Dundalk (Maryland) | 674.09 mi (1,084.85 km) |
| Opelika to Dunedin (Florida) | 355.10 mi (571.48 km) |
| Opelika to Dunkirk (New York) | 754.35 mi (1,214.01 km) |
| Opelika to Dunmore (Pennsylvania) | 808.94 mi (1,301.86 km) |
| Opelika to Dunwoody (Georgia) | 107.74 mi (173.40 km) |
| Opelika to Durango (Colorado) | 1,309.75 mi (2,107.84 km) |
| Opelika to Durant (Oklahoma) | 642.24 mi (1,033.58 km) |
| Opelika to Durham (North Carolina) | 434.66 mi (699.52 km) |
| Opelika to Dyer (Indiana) | 621.69 mi (1,000.52 km) |
| Opelika to Dyersburg (Tennessee) | 326.72 mi (525.81 km) |
