| Opelika to El Segundo (California) | 1,901.14 mi (3,059.60 km) |
| Opelika to El Sobrante (California) | 1,847.98 mi (2,974.03 km) |
| Opelika to Eldersburg (Maryland) | 661.67 mi (1,064.85 km) |
| Opelika to Elfers (Florida) | 345.52 mi (556.06 km) |
| Opelika to Elgin (Illinois) | 667.69 mi (1,074.54 km) |
| Opelika to Elizabeth (New Jersey) | 829.52 mi (1,334.99 km) |
| Opelika to Elizabeth City (North Carolina) | 577.64 mi (929.62 km) |
| Opelika to Elizabethton (Tennessee) | 310.53 mi (499.75 km) |
| Opelika to Elizabethtown (Kentucky) | 349.50 mi (562.47 km) |
| Opelika to Elizabethtown (Pennsylvania) | 710.75 mi (1,143.84 km) |
| Opelika to Elk City (Oklahoma) | 825.69 mi (1,328.83 km) |
| Opelika to Elk Grove (California) | 2,049.66 mi (3,298.61 km) |
| Opelika to Elk Grove Village (Illinois) | 661.39 mi (1,064.40 km) |
| Opelika to Elk Plain (Washington) | 2,172.16 mi (3,495.75 km) |
| Opelika to Elk River (Minnesota) | 978.42 mi (1,574.62 km) |
