| Opelika to Eugene (Oregon) | 2,168.30 mi (3,489.55 km) |
| Opelika to Euless (Texas) | 679.80 mi (1,094.04 km) |
| Opelika to Eureka (California) | 2,200.52 mi (3,541.40 km) |
| Opelika to Eureka (Missouri) | 500.33 mi (805.20 km) |
| Opelika to Eustis (Florida) | 342.53 mi (551.25 km) |
| Opelika to Evans (Colorado) | 1,196.21 mi (1,925.12 km) |
| Opelika to Evans (Georgia) | 197.65 mi (318.09 km) |
| Opelika to Evanston (Illinois) | 660.75 mi (1,063.38 km) |
| Opelika to Evanston (Wyoming) | 1,525.25 mi (2,454.65 km) |
| Opelika to Evansville (Indiana) | 387.59 mi (623.76 km) |
| Opelika to Everett (Massachusetts) | 1,031.44 mi (1,659.94 km) |
| Opelika to Everett (Washington) | 2,179.01 mi (3,506.79 km) |
| Opelika to Evergreen Park (Illinois) | 638.86 mi (1,028.14 km) |
| Opelika to Ewa Beach (Hawaii) | 4,457.33 mi (7,173.37 km) |
| Opelika to Ewa Gentry (Hawaii) | 4,457.89 mi (7,174.29 km) |
