| Opelika to Friendly (Maryland) | 632.18 mi (1,017.40 km) |
| Opelika to Friendswood (Texas) | 620.23 mi (998.17 km) |
| Opelika to Frisco (Texas) | 664.42 mi (1,069.27 km) |
| Opelika to Front Royal (Virginia) | 591.09 mi (951.27 km) |
| Opelika to Fruit Cove (Florida) | 283.79 mi (456.72 km) |
| Opelika to Fruita (Colorado) | 1,377.12 mi (2,216.26 km) |
| Opelika to Fruitville (Florida) | 407.34 mi (655.55 km) |
| Opelika to Fuller Heights (Florida) | 384.42 mi (618.67 km) |
| Opelika to Fullerton (California) | 1,874.41 mi (3,016.58 km) |
| Opelika to Fullerton (Pennsylvania) | 776.19 mi (1,249.15 km) |
| Opelika to Fulshear (Texas) | 653.54 mi (1,051.77 km) |
| Opelika to Fulton (Missouri) | 564.47 mi (908.42 km) |
| Opelika to Fulton (New York) | 882.04 mi (1,419.51 km) |
| Opelika to Fuquay-Varina (North Carolina) | 428.29 mi (689.26 km) |
| Opelika to Gadsden (Alabama) | 100.13 mi (161.15 km) |
