| Opelika to Indianapolis (Indiana) | 493.52 mi (794.24 km) |
| Opelika to Indianola (Iowa) | 751.25 mi (1,209.02 km) |
| Opelika to Indio (California) | 1,778.97 mi (2,862.98 km) |
| Opelika to Inglewood (California) | 1,897.56 mi (3,053.82 km) |
| Opelika to Inkster (Michigan) | 675.00 mi (1,086.31 km) |
| Opelika to Inver Grove Heights (Minnesota) | 935.80 mi (1,506.02 km) |
| Opelika to Inwood (New York) | 845.99 mi (1,361.49 km) |
| Opelika to Iona (Florida) | 471.53 mi (758.85 km) |
| Opelika to Ionia (Michigan) | 712.97 mi (1,147.41 km) |
| Opelika to Iowa City (Iowa) | 707.36 mi (1,138.38 km) |
| Opelika to Irmo (South Carolina) | 260.94 mi (419.94 km) |
| Opelika to Irondale (Alabama) | 96.12 mi (154.70 km) |
| Opelika to Ironton (Ohio) | 433.01 mi (696.86 km) |
| Opelika to Irvine (California) | 1,867.31 mi (3,005.15 km) |
| Opelika to Irving (Texas) | 673.41 mi (1,083.76 km) |
