| Opelika to Isabela (Puerto Rico) | 1,500.86 mi (2,415.40 km) |
| Opelika to Iselin (New Jersey) | 820.23 mi (1,320.03 km) |
| Opelika to Isla Vista (California) | 1,980.16 mi (3,186.75 km) |
| Opelika to Issaquah (Washington) | 2,166.25 mi (3,486.25 km) |
| Opelika to Ithaca (New York) | 831.50 mi (1,338.17 km) |
| Opelika to Ives Estates (Florida) | 558.44 mi (898.72 km) |
| Opelika to Jackson (Michigan) | 664.18 mi (1,068.89 km) |
| Opelika to Jackson (Mississippi) | 282.80 mi (455.13 km) |
| Opelika to Jackson (Missouri) | 405.83 mi (653.12 km) |
| Opelika to Jackson (Tennessee) | 286.06 mi (460.36 km) |
| Opelika to Jackson (Wyoming) | 1,561.57 mi (2,513.10 km) |
| Opelika to Jacksonville (Alabama) | 82.24 mi (132.35 km) |
| Opelika to Jacksonville (Arkansas) | 416.98 mi (671.07 km) |
| Opelika to Jacksonville (Florida) | 271.00 mi (436.14 km) |
| Opelika to Jacksonville (Illinois) | 558.13 mi (898.22 km) |
