| Opelika to Odenton (Maryland) | 656.84 mi (1,057.09 km) |
| Opelika to Odessa (Texas) | 991.69 mi (1,595.98 km) |
| Opelika to Ogden (Utah) | 1,575.28 mi (2,535.17 km) |
| Opelika to Oildale (California) | 1,926.88 mi (3,101.01 km) |
| Opelika to Ojus (Florida) | 559.60 mi (900.58 km) |
| Opelika to Okemos (Michigan) | 695.99 mi (1,120.09 km) |
| Opelika to Oklahoma City (Oklahoma) | 720.68 mi (1,159.82 km) |
| Opelika to Okmulgee (Oklahoma) | 640.80 mi (1,031.27 km) |
| Opelika to Olathe (Kansas) | 681.27 mi (1,096.40 km) |
| Opelika to Old Jamestown (Missouri) | 507.69 mi (817.05 km) |
| Opelika to Oldsmar (Florida) | 357.07 mi (574.65 km) |
| Opelika to Olean (New York) | 753.74 mi (1,213.03 km) |
| Opelika to Olive Branch (Mississippi) | 301.78 mi (485.66 km) |
| Opelika to Olivehurst (California) | 2,059.40 mi (3,314.29 km) |
| Opelika to Olney (Maryland) | 645.07 mi (1,038.14 km) |
