| Opelika to Orangevale (California) | 2,040.94 mi (3,284.58 km) |
| Opelika to Orchards (Washington) | 2,159.35 mi (3,475.13 km) |
| Opelika to Orcutt (California) | 2,008.53 mi (3,232.42 km) |
| Opelika to Oregon (Ohio) | 630.34 mi (1,014.44 km) |
| Opelika to Oregon (Wisconsin) | 742.00 mi (1,194.13 km) |
| Opelika to Oregon City (Oregon) | 2,157.64 mi (3,472.39 km) |
| Opelika to Orem (Utah) | 1,547.61 mi (2,490.64 km) |
| Opelika to Orinda (California) | 2,093.27 mi (3,368.80 km) |
| Opelika to Orland Park (Illinois) | 633.02 mi (1,018.75 km) |
| Opelika to Orlando (Florida) | 375.86 mi (604.88 km) |
| Opelika to Ormond Beach (Florida) | 343.63 mi (553.02 km) |
| Opelika to Oro Valley (Arizona) | 1,487.54 mi (2,393.97 km) |
| Opelika to Oroville (California) | 2,060.50 mi (3,316.06 km) |
| Opelika to Oshkosh (Wisconsin) | 803.58 mi (1,293.23 km) |
| Opelika to Oskaloosa (Iowa) | 717.96 mi (1,155.45 km) |
