| Opelika to Reidsville (North Carolina) | 412.21 mi (663.39 km) |
| Opelika to Reisterstown (Maryland) | 669.52 mi (1,077.50 km) |
| Opelika to Rendon (Texas) | 689.74 mi (1,110.03 km) |
| Opelika to Reno (Nevada) | 1,969.33 mi (3,169.33 km) |
| Opelika to Renton (Washington) | 2,171.63 mi (3,494.90 km) |
| Opelika to Republic (Missouri) | 551.91 mi (888.21 km) |
| Opelika to Reston (Virginia) | 625.03 mi (1,005.88 km) |
| Opelika to Revere (Massachusetts) | 1,034.03 mi (1,664.11 km) |
| Opelika to Rexburg (Idaho) | 1,617.63 mi (2,603.32 km) |
| Opelika to Reynoldsburg (Ohio) | 524.25 mi (843.69 km) |
| Opelika to Rialto (California) | 1,841.98 mi (2,964.38 km) |
| Opelika to Richardson (Texas) | 658.07 mi (1,059.06 km) |
| Opelika to Richfield (Minnesota) | 944.23 mi (1,519.58 km) |
| Opelika to Richfield (Wisconsin) | 747.08 mi (1,202.31 km) |
| Opelika to Richland (Washington) | 2,017.91 mi (3,247.51 km) |
