| Opelika to Saddlebrooke (Arizona) | 1,480.39 mi (2,382.45 km) |
| Opelika to Safety Harbor (Florida) | 359.01 mi (577.77 km) |
| Opelika to Saginaw (Michigan) | 747.36 mi (1,202.77 km) |
| Opelika to Saginaw (Texas) | 696.32 mi (1,120.62 km) |
| Opelika to Sahuarita (Arizona) | 1,491.71 mi (2,400.67 km) |
| Opelika to Saks (Alabama) | 77.65 mi (124.96 km) |
| Opelika to Salem (Massachusetts) | 1,042.05 mi (1,677.01 km) |
| Opelika to Salem (Ohio) | 622.01 mi (1,001.03 km) |
| Opelika to Salem (Oregon) | 2,173.18 mi (3,497.40 km) |
| Opelika to Salem (Virginia) | 439.03 mi (706.55 km) |
| Opelika to Salem Lakes (Wisconsin) | 698.66 mi (1,124.39 km) |
| Opelika to Salida (California) | 2,033.76 mi (3,273.02 km) |
| Opelika to Salina (Kansas) | 806.20 mi (1,297.45 km) |
| Opelika to Salinas (California) | 2,066.43 mi (3,325.60 km) |
| Opelika to Salisbury (Maryland) | 676.86 mi (1,089.31 km) |
